8-K Impact 6/10 Buyback / Leadership Change

$ALNY · ALNYLAM PHARMACEUTICALS, INC.

November 5, 2026 · AI-analyzed SEC filing · Verify material figures against the official SEC.gov filing

Alnylam filed an 8-K disclosing two items: a board-authorized $1.0 billion common stock repurchase program (the "2026 Repurchase Program") and the December 2026 departure of EVP and Chief Commercialization Officer Tolga Tanguler. The company anticipates repurchasing roughly $500 million by end of 2026 and the remainder during 2027, with no expiration date and full discretion to modify or suspend. Tanguler and the company intend to enter a written separation agreement by his separation date.

  • Board authorized up to $1.0 billion in common stock repurchases under the 2026 Repurchase Program.
  • Company expects ~$500 million of buybacks by end of 2026 and the balance during 2027.
  • Program has no expiration date and may be modified, suspended, or discontinued at any time.
  • CCO Tolga Tanguler will depart in December 2026; a written separation agreement is pending.
  • Repurchases may occur via open market, 10b5-1 plans, or privately negotiated transactions.

Extended-hours last trade of $168.00 is +4.30% vs the $161.08 regular close, suggesting a positive initial reaction to the buyback authorization.

A $1.0 billion buyback signals capital-return confidence, though the concurrent CCO departure adds a leadership-transition watch item.

_Not applicable._

The buyback is discretionary and may be suspended or discontinued; the separation agreement with Tanguler has not yet been finalized.

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