$TMO · Thermo Fisher Scientific Inc.

This Form 4 filing reports a change in beneficial ownership for Scott M. Sperling, a director and 10% owner of Thermo Fisher Scientific Inc. On September 26, 2026, Sperling acquired 62.96 phantom stock units under the company’s Deferred Compensation Plan for Directors at $675.00 per unit. The units convert into common stock on a one-for-one basis. They represent the quarterly deferral of his director retainer, credited based on the closing price of the common stock at quarter end.

After the transaction, Sperling directly held 17,737.6 phantom stock units. The units are distributable as common stock upon the cessation of his director service for any reason or upon a change of control. The filing reports no sale or disposition of securities. It was signed by an attorney-in-fact on September 29, 2026.